Each gram contains Lidocaine Hydrochloride USP 20 mg

Z-LIDOCAINE Jelly : is a sterile local anaesthetic product which contains Lidocaine Hydrochloride  USP  in  a  water-soluble  Jelly  base.  It  is  used  for  topical/surface anaesthesia.  The  onset  of  action  is  3-5  minutes.  It  may  be  rapidly  and  almost completely  absorbed  following  topical  application  to  mucous  membrane  and systemic eects may occur.

Z-LIDOCAINE  Jelly   is  indicated  for  surface  anaesthesia  of  the  male  and  female  urethra, topical treatment of painful urethritis, anaesthetic lubrication for endotracheal intubation and for adequate analgesia in endoscopy.

DIRECTION FOR USE
Urethral anaesthesia :
♦ Surface anaesthesia of the male adult urethra : For adequate  
     analgesia in males 400 mg is required.
♦ Surface anaesthesia of the female adult urethra : Instil 100-200 mg  
   in small portions to ll the whole urethra. In order to obtain adequate  
     anaesthesia, several minutes should be allowed prior to perform in  
     urological procedure.

Lubrication for endotracheal intubation : 100 mg applied on the surface of   the tube just prior to insertion. Care should be taken to avoid  introducing the  product into the lumen of the tube.

Endoscopy: Instillation of 200-400 mg is recommended for adequate  
analgesia and a small amount should be applied on the instrument for  
lubrication. Debilitated, elderly patients and children should be given doses commensurate  with their age and physical condition.
Note:  The applicator is sterilized for 5 minutes in boiling water, cooled and attached to  the  tube.  The  jelly  is  instilled  slowly  as  required.  The  applicator  should  be  
detached after each use and keep the tube tightly closed.

Nervousness, dizziness,     blurred     vision,     tremors,     drowsiness,     convulsions,  unconsciousness, respiratory arrest, hypotension, myocardial depression, bradycardia, cardiac arrest and anaphylactic reactions (cutaneous lesion, urticaria, oedema).

Absorption   from   wound   surfaces   and   mucous   membranes   is   relatively   high, especially  in  the  bronchial  tree.  Lidocaine  Jelly  should  be  used  with  caution  in  patients  with  traumatised  mucosa  and/or  sepsis  in  the  region  of  the  proposed  application.If the dose or site of administration is likely to result in high blood levels, Lidocaine, in common with other local anaesthetics, should be used cautiously in patients with epilepsy, impaired cardiac condition, bradycardia, impaired hepatic function and in severe shock.The use of oropharyngeal topical anaesthetic agents may interfere with swallowing and thus enhance the danger of aspiration. This is particularly important in children because  of  their  frequency  of  eating.  Numbness  of  the  tongue  or  buccal  mucosa  may increase the danger of biting trauma.

Keep out of the reach of children

It  is  contraindicated  in  patients  with  a  known  history  of  hypersensitivity  of  local
anaesthetics of the amide type

There is no, or inadequate, evidence of safety of the drug in human pregnancy but it  has  been  in  wide  use  for  many  years  without  apparent  ill  consequence.  If  drug therapy is needed in pregnancy, this drug can be used if there is no safer alternative. Lidocaine enters the mother's milk, but in such small quantities that there is generally  no risk of aecting the child at therapeutic dose levels.

Tube containing 30 g Jelly with a detachable applicator in each package

Lidocaine should be used with caution in patients receiving antiarrhythmic drugs,such as tocainide, since the toxic eects are additive.

Store below 25°C in a dry place, away from light.